The most common cause of hereditary breast cancer is a mutation in either the BRCA1
or BRCA2 gene. Individuals with mutations in these genes have Hereditary Breast a
nd Ovarian Cancer Syndrome (HBOC). Risk factors for this syndrome include any of the following in
a patient or their family:
- Female breast cancer prior to age 50 (or at any age, if Ashkenazi Jewish descent)
- Male breast cancer (at any age)
- Ovarian cancer (at any age)
- Two or more of these cancers in a person or family (at any age)
More detailed criteria for BRCA1 and BRCA2 genetic testing can be found on
the
National Comprehensive Cancer Network (NCCN) website.
Individuals with HBOC are at a very high risk to develop breast and ovarian cancer. As a result,
they should undergo different screening and consider different medical management options. Genetic
testing is the only way to determine whether someone has HBOC. If a patient is aware of this
diagnosis, he or she has the chance to significantly decrease the risk of cancer, if not prevent it
completely.
Cancer genetic testing is a very scientific process but often patients have many questions about
it. Additionally, genetic test results can be complex to interpret and a genetic counselor can help
patients understand what the results mean for them and their relatives. A patient who is interested
in scheduling a visit with the genetic counselor at Invision Sally Jobe should contact Centralized
Scheduling at (720) 493-3226. For more information, please view our Frequently
Asked Questions about genetic counseling appointments. Patients with general questions can
call 720-493-3700 or send an email to RAPP@riaco.com.
Relevant Resources